"Exceptionally Brash" made a comment which didn't particularly "click" with me when i first read it, but DID this morning. She observed that the use of bioidentical progesterone seemed to "fix" her ability to use carbohydrates in a "normal" way (my phrasing). Remember, she was a lean vegetarian for many years, then with midlife hormonal changes began to gain weight on the same intake that she maintained with before.
The discussion seems to me to settle on dopamine as the final substance which wrought the desirable end-product, but i wonder if testosterone might be a part of the equation. It occurs to me that the paleo world's "potato brigade" is peopled largely by the highly-T-endowed amongst us....
Since going out of town a couple of weeks ago, i have been abnormally low in energy. It's as though to have even MY usual levels of vitality, i need to have every nutrient in proper quantity and balance just like a house of cards -- and one puff of wind (in the form of a deficiency, or too many carbs, or too little sleep...) can tumble it right down. The tedious rebuilding of my Edifice of Energy can take a LONG TIME ... and i'm just beginning the second story at this point.
I'm going to try yet another experiment. Adding tyrosine made me hyper instead of energetic, and carnitine was less than perfect too, though i'm still using both supplements albeit in smaller, less frequent doses. I just ordered some sublingual pregnenolone tablets as suggested by Drs Peat and Sahelian (not that these guys are on my go-to list), and i'm interested to see what the effects will be. Ideally, it will be a better supplement than the progesterone cream i've used before, which tends to promote fat deposition on the location where it's applied!