Life is a continuing experiment, with me.... I constantly juggle different supplements which i found to be useful in the past ... and new ones that sound promising. THIS TAKES A LO-O-O-ONG TIME. :-) IF you don't take your time testing your supplements, you don't know if you've taken them long ENOUGH. Some leap into action in the body, and others take their bloody sweet time getting to work. If you add new supplements too close to one another, you don't know what is doing what -- they could conceivably cancel each other out, or exacerbate the other's properties so you conclude they're not tolerable.
Pyrroloquinoline quinone (pqq) was a new one i tried -- theoretically, it helps with the creation of new mitochondria. I found no benefit from it. If i HAVE more new mitos from using this substance, they're so few or so wimpy it certainly isn't worth cultivating them.
I tried 7-keto last year, and didn't think i was getting anything from it, so i stopped. Then, before going out of town at christmastime, i decided to what-the-hell-finish-them-up. To my surprise, i felt as though the excess junk i ate (excuse -- there were children and other indulgers around) didn't pile the fat on, as i would have expected! YEA! I finished the bottle, but didn't re-order right away -- after all, when i went back home (and even on our N'Orleans trip in January) i consumed an exemplary diet, so the need wasn't so urgent ... and any excuse to take fewer pills is good. ;-) Recently, wanting to shed weight faster for the summer, i ordered another bottle, and DAMMIT it's "not working" again! From what i read, i know that seasonal weight and hormone fluctuations are real and formidable phenomena. It kinda looks like however 7-keto functions, there's a tie-in with this seasonal issue! Damned if i know what it is, but ... ;-) ... i think i'll put this supplement in the anti-autumnal-fat-storage arsenal!
I took a holiday from the pregnenolone, thinking i'd let nature take its natural course and see what happened. I ended up with perceived lower energy, so decided to start again ... and felt overstimulated. Halving the dose seems to be helping a bit.
Liquid carnitine is absolutely positively necessary for me having ANY energy at all. There are voices out there which scream that this should not be happening, that carnitine inhibits thyroid binding to receptors!!! THIS IS OBVIOUSLY NOT TRUE.
You know the truism, that since you can use starvation to reduce fat stores, CICO must be "true"? OF COURSE you do, or you would probably not be reading this! ;-) Well, since they used to use carnitine to stop "thyroid storm," Conventional Wisdom claims that carnitine actually inhibits thyroid entering cells. I think they got it wrong -- if this were true, i'd feel like SHIT, not energized.
Something else has got to be happening. There's no other REASONABLE conclusion. Does carnitine perform an adaptogenic function? It has been shown to "escort" fatty acids into cells for burning -- AND SO DOES T3. Does carnitine take over this job when its concentration in the body is high enough? In this case, does T3 get spared for doing other work? God only knows, and the scientific community -- who could find out -- doesn't give a shit. They've made up their mind and they fight tooth-and-nail not to change it ... even people who you'd think would know better.
The liquid form of carnitine is SIGNIFICANTLY more effective for me than the capsule. Dunno why, just IS.
Despite taking a goodly dose of zinc every evening, i've had a few zinc-depletion symptoms recently (since suffering that bout of food-poisoning in March, to be exact). I've JUST started taking it in the morning instead of the evening, to see what happens....
Some time ago, i ordered some Lipophos Forte ... but i keep forgetting to take it, because it "lives" in the kitchen, and i'm always busy when i see the jar and think "hmmm, ... later." I need to relocate it, i guess, to give it a fighting chance of working!
Last night, i ordered some SAMe after reviewing some of my methylation literature. The other supplements suggested by van Konynenburg have been very helpful, but my energy is still subnormal so it's time to take the next step!
Beyond these, i'm still taking the thyroid-support supplement that's SO GOOD, and cod-liver-oil as needed to balance diet, iron/copper and K2 ditto, and glutathione/Bcomplex, AND sublingual methylcobalamin ....
And MAGNESIUM. That's important. ;-) ...Damn, i swallow a lot of pills and liquids. No wonder i'm rarely really hungry.