In my search for improved health and energy, I started using van Konynenburg's simplified protocol to improve function of the methylation cycle. When time permits, I try to read more on the subject; I finally bought a book by Dr. Amy Yasko, "Feel Good Nutrigenomics."
My review? Don't bother -- go straight to her website and download (free) "Autism: Pathways to Recovery." She had professional writing help, which looks like it removed a lot of the stuff in the nutrigenomics work which made it so hard for me to read -- stuff like using the word "tenant" where she should have used "tenet" -- one of my pet peeves! Little things like that drive my OCD brain frantic!
It helps that I got my SNPs analyzed at 23andMe. I'm assured, as I merely suspected before, that my methylation is out-to-lunch -- i'm MTHFRed bigtime! ;-)
I had already started using methyl-B12 long before any of the other supplements, so I didn't accidentally get things out of sequence (see what I wrote earlier about "doing it wrong" and understand how easily I could have been one of the wrong-doers...). The B-Right supplement was just what I needed, when I needed it. And the mega-glutathione!!! OMG, it was the best thing that happened to me since Iodoral -- I started feeling better the same afternoon!
Well, today I just started reading the autism book, and my SAMe supplement also arrived in the mail -- I have a sneaking suspicion that it will be as Rick said at the end of "Casablanca" -- the beginning of a beautiful friendship.