Dr. Perlmutter's latest blog post discusses a study in the journal Neurology, in which MRIs showing deleterious brain changes are analyzed in relation to "various markers of blood fats and risk." The verdict: lower LDL is not a good thing. If you haven't read it already, I encourage you to.
I have the perfect anecdote about why this is news we should have had a long time ago -- before low-fat dietary advice fucked up the health of America (and probably a lot of the rest of the world). It's a comparatively recent tragedy involving my mother's dearest friend.
Mother was the executive-secretary for the head of the pharmacology department of KUMC for decades. She particularly got along with a most remarkable doctor there, Stata Norton, and after they had both retired, they continued and deepened their friendship. I knew, liked, and had an immense amount of respect for Stata!
If there's a fault to be found in the thinking of extremely brilliant professionals, it's probably that they believe their peers are as brilliant -- and honest -- as they are. Somewhere along the line, Dr. Norton heard and gave credence to the bullshit about low-fat and low-sodium and health -- she put herself and her chubby husband (Dr. David Ringle, from the pathology department of the same institution) on low-fat diets. I mean LOWWWWW fat. Mother used to say that Stata had been a good cook, and looked forward to her Christmas cake, until she ruined it by removing the butter.
Dr. Ringle (I never knew him as well as I did Stata, so never felt comfortable about referring to him as Dave) started losing his wits. At first, Mother used to attribute it to the geek factor (not that she used that term) -- not having first-rate conversational skills, but a decidedly odd sense of humor. But then he started forgetting things more and more; it was obviously dementia. I believe he had a stroke at some point too, but my memory is less clear on that score. At last, it looked like his mind was totally gone, and he was going to have to go into an institution.
He was in the hospital, and the dog-sitter arrived one morning to find Stata dead on the sofa from a self-inflicted gunshot wound.
There is absolutely no doubt in my mind these two able and respected scientists met premature ends because of the FALLACIOUS INFORMATION from ego- and profit-motivated sources. When I rage against those FUCKING LIARS, there's definitely a personal aspect to my fury.