Reading other discussions on what glutathione is, where it comes from, what it's good for and so on, i happened across an important note! It seems that when supplementing this important chemical, people often need more zinc, which has itself been the topic of conversation at the Scribble Pad recently. Now, zinc is a VERY important mineral in the thyroid world, and one which even a lot of "normal, healthy" people tend to be a little short of ... and a significant shortage WILL make you miserable.
THIS is why running out and impulsively adding supplements to one's regimen can be a big mistake. I suppose this is why a lot of proponents of supplementation insist that one should work with one's physician in tweaking nutrients, too -- though the shortcoming with this notion is that most doctors are more ignorant about nutrients than the "interested amateur." One has to do quite a bit of extra reading to find information such as the glutathione-zinc connection, and that kind of rabbit-trail tracking is time-consuming and nerdier than most professionals care for.
It's been suggested that hypothyroid people who have had trouble with iodine started supplementing too lavishly or without having their selenium bases covered. I'm in no position to make judgements on the situation, but it IS a valid question to ask. So many vitamins, minerals and aminos don't operate as lone-wolves; they need their mates or their entire packs to help do their jobs properly. Unless one does some pretty extensive homework, "details" like balancing one's A and D are totally overlooked, and some ugly little results can appear.
The homework necessary for success in tweaking one's health through supplementation is far more demanding than merely cleaning up one's diet paleo-style. A significant variety of sources needs to be accessed, because a lot of websites quote each other without doing THEIR homework! I look at conventional sources like WebMD and the Mayo Clinic sites (and many others) just to attempt to find VALID naysayers to what i've found in "alternative" circles. I occasionally read some of the wingnuts too, even if i take their recommendations with quite a few grains of (unrefined sea) salt.
When we become disillusioned with mainstream medicine and seek to be our OWN arbiters of wellness, we take a responsibility that most sheeple don't. If good health is our goal (and what else COULD be our aim?), then we have to go the EXTRA distance to learn things that conventionally-trained medical personnel picked up in the course of their educations -- what we excitedly observe as a big revelation is often a "duh moment" for them. On the other hand, we have a greater incentive to get it right for our particular situation and genome, and to them we're just another statistic or victim of probabilities.
Short version? (Too late....) Don't be in a hurry to invest in the (usually expensive) supplement-du-jour without doing a LOT of reading in a variety of sources! Just because Oz (or Mercola or Kruse or Rosedale) makes a "new" nutrient or superfood sound like the answer to prayer, checking up with somebody who could easily be an "anti" might be the best idea you ever had.
Don't believe ME, either. ...Oh, okay, believe that what i say is what I EXPERIENCED (because i have no incentive or desire to lie about it), but don't believe that what works with me will work for YOU, till you do your own checking up and careful experimentation. ;-)