Today i followed a link i discovered some time ago, and it has put me onto a tangent i can believe in. It speaks of the deiodinases which convert T4 to 3 (and also to rT3), and D1 is shorthand for the deiodinase which contributes largely to SYMPTOMATIC hypothyroidism when it's in reduced supply. One's T4 can be in an acceptable range, and peripheral T3 can be too low as a result. There's quite a laundry-list of things which inhibit our D1....
The conclusions drawn in the article are NOT what i find interesting here. THEY say, because of the actions of these Ds, to be healthy the patient's TSH number is immaterial and if there's not enough free T3 ... GIVE 'EM MORE DRUGS! We want our DRUUUUUUGGGGS!!! MO-O-O-O-ORE TEE-THREEEEEE!!!!!
As they say down in Texas -- sheeee-YIT! I know people want to feel normal, but did it never occur to them that the body is dialing down on thyroid conversion for a reason?
A few of the things that suppress D1 (and which they discussed in the article) are:
- physiologic and emotional stress;
- weight gain and leptin resistance;
- insulin resistance, obesity and diabetes;
- inflammation from autoimmune disease or systemic illness;
- chronic fatigue syndrome and fibromyalgia;
- chronic pain; and
- exposure to toxins and plastics.
The body OBVIOUSLY wants us to slow down when these destabilizing causes are in action! It wants us to fix what's the matter, not carry on as if nothing were wrong. Remove the poisons, heal the injuries, outwear the stressor while getting extra rest, increase omega3 and hang around upbeat friends to help inflammation and mood, and ... FGS stop calorie-restricted dieting!
One thing i find marvelous about LCHF is that i'm "never" hungry. Assuming i eat the right foods, i can eat to fullness in two to three meals, i'm not tempted to snack, and i don't gain weight. I just CAN'T consume those "excess" calories that CICO-enthusiasts are so fond of condemning -- there's no room. Entering my intake in FitDay reveals to me that while eating this way, i spontaneously eat from 1200 to 2200 calories per day, with between half and three-quarters of them from fats. I guess some people would call that low end "calorie restricted" but since i'm not consciously trying to do so, and it doesn't happen every day, i don't believe it would be accurate to call it CR.
Apparently, a thyroid-challenged person HAS to find non-toxic foods that will satisfy without causing her/him to gain, if T3 values are to remain within an acceptable range. And while i would object to telling hypothyroids "don't diet!" if they have excess fat that is burdening their systems, i know damn well that choosing a reducing diet careful is in their best interests! ... I also hope that they'll exercise reasonable skepticism about the absurd promotion of a LFHC diet for their condition!
* while trying to ascertain the proper spelling of "sloo" -- whether it's slough or slew -- dictionary.com informed me that this americanism derived from an irish word. therefore i'll honor the source by spelling the original way. erin go bragh! ;-)